Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50063283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063283 ((4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...) Show SMILES COc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1 |wU:17.21,wD:14.14,(20.52,-8.07,;19.67,-6.75,;18.13,-6.85,;17.27,-5.56,;15.74,-5.65,;15.06,-7.01,;15.89,-8.3,;17.43,-8.23,;13.51,-7.1,;12.82,-8.49,;11.27,-8.56,;10.43,-7.27,;8.88,-7.34,;8.04,-6.05,;6.51,-6.12,;5.67,-4.83,;4.13,-4.9,;3.42,-6.29,;4.26,-7.57,;5.81,-7.5,;1.87,-6.36,;1.03,-5.04,;1.76,-3.69,;.91,-2.37,;-.63,-2.44,;-1.34,-3.83,;-.49,-5.14,;11.13,-5.89,;12.67,-5.82,)| Show InChI InChI=1S/C23H33N5O/c1-29-22-9-7-21(8-10-22)28-17-15-27(16-18-28)14-11-19-3-5-20(6-4-19)26-23-24-12-2-13-25-23/h2,7-10,12-13,19-20H,3-6,11,14-18H2,1H3,(H,24,25,26)/t19-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
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