Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50063288'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063288 (CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...) Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1ncccn1 |wU:2.1,wD:5.5,(2.36,-7.7,;3.06,-6.33,;4.6,-6.26,;5.31,-4.88,;6.85,-4.81,;7.69,-6.11,;9.22,-6.03,;10.06,-7.32,;11.6,-7.25,;12.3,-5.87,;13.84,-5.8,;14.68,-7.08,;13.98,-8.46,;12.44,-8.54,;16.22,-7,;16.9,-5.63,;18.43,-5.54,;19.28,-6.83,;18.58,-8.19,;17.05,-8.28,;6.99,-7.48,;5.45,-7.55,;2.22,-5.03,;.7,-5.12,;-.14,-3.82,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| Show InChI InChI=1S/C23H33N5/c1-26(23-24-13-5-14-25-23)21-10-8-20(9-11-21)12-15-27-16-18-28(19-17-27)22-6-3-2-4-7-22/h2-7,13-14,20-21H,8-12,15-19H2,1H3/t20-,21-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair