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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50119983'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50119983
PNG
(2-[4-(5-Chloro-2-isopropyl-benzyl)-piperazin-1-yl]...)
Show SMILES CC(C)c1ccc(Cl)cc1CN1CCN(CC(=O)N2[C@H](C)Cc3ccccc23)CC1
Show InChI InChI=1S/C25H32ClN3O/c1-18(2)23-9-8-22(26)15-21(23)16-27-10-12-28(13-11-27)17-25(30)29-19(3)14-20-6-4-5-7-24(20)29/h4-9,15,18-19H,10-14,16-17H2,1-3H3/t19-/m1/s1
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 218n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Binding affinity towards Dopamine type 2 receptor was determined by displacement assays using [3H]-YM 09151 as the competitive ligand

Bioorg Med Chem Lett 12: 3111-5 (2002)


BindingDB Entry DOI: 10.7270/Q2DZ07ND
More data for this
Ligand-Target Pair