BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50130290'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 1278-87 (2005) Article DOI: 10.1124/jpet.105.092155 BindingDB Entry DOI: 10.7270/Q2Z60MNB
ACADIA Pharmaceuticals Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Mol Psychiatry 3: 123-34 (1998) Article DOI: 10.1038/sj.mp.4000336 BindingDB Entry DOI: 10.7270/Q2G15ZCQ
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Neuropsychopharmacology 16: 93 (1997) Article DOI: 10.1016/S0893-133X(96)00187-X BindingDB Entry DOI: 10.7270/Q2513WR8
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 1403-10 (1994) BindingDB Entry DOI: 10.7270/Q2154FJQ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals Curated by PDSP K_i Database									J Pharmacol Exp Ther 315: 1278-87 (2005) Article DOI: 10.1124/jpet.105.092155 BindingDB Entry DOI: 10.7270/Q2Z60MNB
ACADIA Pharmaceuticals Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition constant for in vitro inhibition of [3H]spiperone binding to striatal membranes Dopamine receptor D2				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7JSX
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested in vitro for its ability to inhibit [3H]spiperone binding to Dopamine receptor D2 in rat striatal membrane				Citation and Details BindingDB Entry DOI: 10.7270/Q2DJ5HTQ
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVO Industri A/S Curated by PDSP K_i Database									Eur J Pharmacol 146: 113-20 (1988) Article DOI: 10.1016/0014-2999(88)90492-x BindingDB Entry DOI: 10.7270/Q21R6P1H
NOVO Industri A/S Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP K_i Database									Neuropsychopharmacology 28: 519-26 (2003) Article DOI: 10.1038/sj.npp.1300027 BindingDB Entry DOI: 10.7270/Q2833QKK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Mol Pharmacol 12: 800-12 (1976) BindingDB Entry DOI: 10.7270/Q22B8WH6
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Mol Pharmacol 12: 800-12 (1976) BindingDB Entry DOI: 10.7270/Q22B8WH6
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Mol Pharmacol 12: 800-12 (1976) BindingDB Entry DOI: 10.7270/Q22B8WH6
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Mol Pharmacol 12: 800-12 (1976) BindingDB Entry DOI: 10.7270/Q22B8WH6
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic and Foundation Curated by PDSP K_i Database									Eur J Pharmacol 103: 197-204 (1984) Article DOI: 10.1016/0014-2999(84)90478-3 BindingDB Entry DOI: 10.7270/Q2WW7G5B
Mayo Clinic and Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic and Foundation Curated by PDSP K_i Database									Ann N Y Acad Sci 537: 435-42 (1988) Article DOI: 10.1111/j.1749-6632.1988.tb42125.x BindingDB Entry DOI: 10.7270/Q2X065JH
Mayo Clinic and Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50130290 (3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-te...) Show SMILES CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Synapse 25: 137-46 (1997) Article DOI: 10.1002/(SICI)1098-2396(199702)25:2 BindingDB Entry DOI: 10.7270/Q2WH2NH6
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair