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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50190087'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50190087
PNG
(8-chloro-11-[4-(2,2-difluoro-benzo[1,3]dioxol-4-yl...)
Show SMILES FC1(F)Oc2cccc(CN3CCN(CC3)C3=Nc4cc(Cl)ccc4Nc4ccccc34)c2O1 |t:17|
Show InChI InChI=1S/C25H21ClF2N4O2/c26-17-8-9-20-21(14-17)30-24(18-5-1-2-6-19(18)29-20)32-12-10-31(11-13-32)15-16-4-3-7-22-23(16)34-25(27,28)33-22/h1-9,14,29H,10-13,15H2
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8n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute K15 2545

Curated by ChEMBL


Assay Description
Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cells


Bioorg Med Chem Lett 16: 4548-53 (2006)

Checked by Author
Article DOI: 10.1016/j.bmcl.2006.06.034
BindingDB Entry DOI: 10.7270/Q2MG7P4R
More data for this
Ligand-Target Pair