Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50285668 (2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Binding affinity to dopaminergic D2 receptor (unknown origin) | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50285668 (2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to dopamine D2 receptor (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-012-0055-5 BindingDB Entry DOI: 10.7270/Q2959MG8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50285668 (2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity towards cloned human Dopamine D2 receptor in CHO cells using [3H]-spiperone as radioligand | Bioorg Med Chem Lett 5: 2547-2550 (1995) Article DOI: 10.1016/0960-894X(95)00447-2 BindingDB Entry DOI: 10.7270/Q20R9PCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50285668 (2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatum homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair |