Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM141765'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM141765 (US8921397, 7) Show SMILES CS(=O)(=O)CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1 |r,wU:11.11,wD:8.7,(9.95,-1.33,;9.18,,;10.51,.77,;7.84,-.77,;8.41,1.33,;6.87,1.33,;6.1,2.67,;6.1,,;4.56,,;3.79,1.33,;2.25,1.33,;1.48,,;-.06,,;-.83,-1.33,;-2.37,-1.33,;-3.14,-2.67,;-4.68,-2.67,;-5.45,-1.33,;-4.68,,;-3.14,,;-6.99,-1.33,;-7.9,-2.58,;-9.36,-2.1,;-9.36,-.56,;-10.51,.47,;-10.19,1.97,;-8.72,2.45,;-7.58,1.42,;-7.9,-.09,;2.25,-1.33,;3.79,-1.33,)| Show InChI InChI=1S/C24H34N2O4S/c1-31(28,29)17-24(27)25-20-8-6-18(7-9-20)10-13-26-14-11-19(12-15-26)22-16-30-23-5-3-2-4-21(22)23/h2-5,16,18-20H,6-15,17H2,1H3,(H,25,27)/t18-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description liquots of membrane preparations were thawed at RT, resuspended in assay buffer (D2, D3: 50 mM Tris-HCl, 120 mM NaCl, 5 mM MgCl2, 1 mM EDTA, 5 mM KC1...				US Patent US8921397 (2014) BindingDB Entry DOI: 10.7270/Q2VQ31C3
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