BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50054067'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description In vitro binding affinity at human Dopamine receptor D3 expressed in CHO K1 cells was measured by its ability to displace [3H]spiperone				J Med Chem 45: 3022-31 (2002) BindingDB Entry DOI: 10.7270/Q2QC047Q
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.				J Med Chem 39: 4233-7 (1996) Article DOI: 10.1021/jm960345l BindingDB Entry DOI: 10.7270/Q21C1XJF
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.				Bioorg Med Chem Lett 7: 2403-2408 (1997) Article DOI: 10.1016/S0960-894X(97)00443-5 BindingDB Entry DOI: 10.7270/Q27W6CQ0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells				J Med Chem 46: 4377-92 (2003) Article DOI: 10.1021/jm030085p BindingDB Entry DOI: 10.7270/Q21V5FPS
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 51: 101-17 (2008) Article DOI: 10.1021/jm070860r BindingDB Entry DOI: 10.7270/Q2VQ32FD
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in HEK293 cells				J Med Chem 53: 1023-37 (2010) Article DOI: 10.1021/jm901184n BindingDB Entry DOI: 10.7270/Q29023VM
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair