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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50408397'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50408397
PNG
(CHEMBL353642)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C25H25BrF3N3O2/c1-34-23-20-8-3-2-7-19(20)22(26)16-21(23)24(33)30-9-10-31-11-13-32(14-12-31)18-6-4-5-17(15-18)25(27,28)29/h2-8,15-16H,9-14H2,1H3,(H,30,33)
PDB

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Similars
Article
PubMed
 251n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki

J Med Chem 40: 833-40 (1997)


Article DOI: 10.1021/jm9605952
BindingDB Entry DOI: 10.7270/Q23J3F5T
More data for this
Ligand-Target Pair