Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50378428'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit B (Streptococcus pneumoniae)	BDBM50378428 (CHEMBL578120) Show SMILES CCNC(=O)Nc1cn2c(cc(cc2n1)-c1cccnc1)-c1ncc(CC)cn1 Show InChI InChI=1S/C21H21N7O/c1-3-14-10-24-20(25-11-14)17-8-16(15-6-5-7-22-12-15)9-19-26-18(13-28(17)19)27-21(29)23-4-2/h5-13H,3-4H2,1-2H3,(H2,23,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assay				Bioorg Med Chem Lett 19: 5302-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.141 BindingDB Entry DOI: 10.7270/Q23X87KD
					More data for this Ligand-Target Pair