Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg... | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 m... | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 60 mins | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50241570 ((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta after 60 mins in presence of 0.1 mg/mL BSA | J Nat Prod 63: 1356-60 (2000) BindingDB Entry DOI: 10.7270/Q2X066S2 | |||||||||||
More data for this Ligand-Target Pair |