Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase, mitochondrial (Homo sapiens (Human)) | BDBM50236025 (CHEMBL2016761 | US11149049, No. C2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Inhibition of human mitochondrial RNA polymerase after 30 mins in presence of [33P]GTP | J Med Chem 60: 1648-1661 (2017) Article DOI: 10.1021/acs.jmedchem.6b01594 BindingDB Entry DOI: 10.7270/Q2QZ2D7N | |||||||||||
More data for this Ligand-Target Pair |