new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'DOPAMINE' and Ligand = 'BDBM50022052'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DOPAMINE


(RAT)
BDBM50022052
PNG
(1-Benzyl-6-chloro-2-methyl-1,2,3,4-tetrahydro-isoq...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2C1Cc1ccccc1
Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-10-15(18)17(20)11-14(13)16(19)9-12-5-3-2-4-6-12/h2-6,10-11,16,20H,7-9H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
53n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Binding affinity of compound towards dopamine (D1) receptor using [3H]-SCH-23,390 was determined in rat striatal membranes


J Med Chem 37: 4317-28 (1995)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2NC607Q
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50022052
PNG
(1-Benzyl-6-chloro-2-methyl-1,2,3,4-tetrahydro-isoq...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2C1Cc1ccccc1
Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-10-15(18)17(20)11-14(13)16(19)9-12-5-3-2-4-6-12/h2-6,10-11,16,20H,7-9H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
53n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nM


J Med Chem 31: 1941-6 (1988)


BindingDB Entry DOI: 10.7270/Q20002PD
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50022052
PNG
(1-Benzyl-6-chloro-2-methyl-1,2,3,4-tetrahydro-isoq...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2C1Cc1ccccc1
Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-10-15(18)17(20)11-14(13)16(19)9-12-5-3-2-4-6-12/h2-6,10-11,16,20H,7-9H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
287n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine (D1) receptor using [3H]-spiperone was determined in rat striatal membranes


J Med Chem 37: 4317-28 (1995)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2NC607Q
More data for this
Ligand-Target Pair