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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM50175734'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50175734
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-...)
Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1nccs1)c1ccccc1
Show InChI InChI=1S/C24H24N4S/c1-3-7-20(8-4-1)19-28-17-13-25-22(28)24(21-9-5-2-6-10-21)11-15-27(16-12-24)23-26-14-18-29-23/h1-10,13-14,17-18H,11-12,15-16,19H2
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PC cid
PC sid
UniChem
Article
PubMed
79n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50175734
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-...)
Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1nccs1)c1ccccc1
Show InChI InChI=1S/C24H24N4S/c1-3-7-20(8-4-1)19-28-17-13-25-22(28)24(21-9-5-2-6-10-21)11-15-27(16-12-24)23-26-14-18-29-23/h1-10,13-14,17-18H,11-12,15-16,19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 98n/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair