BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM50193543'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50193543
PNG
(N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamin...)
Show SMILES COc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccccc1Cl |TLB:4:5:24:8.14.13,18:19:24:8.14.13|
Show InChI InChI=1S/C30H31ClN2O4/c1-36-23-10-8-20-16-24-30(32-25(35)11-9-19-4-2-3-5-21(19)31)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-18-6-7-18/h2-5,8-11,18,24,28H,6-7,12-17H2,1H3,(H,32,35)/b11-9+/t24?,28-,29-,30+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.20n/an/an/an/an/an/an/an/a



University of Bristol

Curated by ChEMBL


Assay Description
Binding affinity to DOR in guinea pig brain membrane


J Med Chem 49: 5333-8 (2006)


Article DOI: 10.1021/jm0604777
BindingDB Entry DOI: 10.7270/Q2WH2QSM
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50193543
PNG
(N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamin...)
Show SMILES COc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccccc1Cl |TLB:4:5:24:8.14.13,18:19:24:8.14.13|
Show InChI InChI=1S/C30H31ClN2O4/c1-36-23-10-8-20-16-24-30(32-25(35)11-9-19-4-2-3-5-21(19)31)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-18-6-7-18/h2-5,8-11,18,24,28H,6-7,12-17H2,1H3,(H,32,35)/b11-9+/t24?,28-,29-,30+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 18n/an/an/an/a



University of Bristol

Curated by ChEMBL


Assay Description
Stimulation of [35S]GTP-gamma-S binding to human recombinant DOR


J Med Chem 49: 5333-8 (2006)


Article DOI: 10.1021/jm0604777
BindingDB Entry DOI: 10.7270/Q2WH2QSM
More data for this
Ligand-Target Pair