Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University La Sapienza Curated by ChEMBL | Assay Description Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranes | J Med Chem 48: 3372-8 (2005) Article DOI: 10.1021/jm040894o BindingDB Entry DOI: 10.7270/Q2X92C3R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me... | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b01327 BindingDB Entry DOI: 10.7270/Q2RB7870 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation counting | J Med Chem 60: 9407-9412 (2017) Article DOI: 10.1021/acs.jmedchem.7b01363 BindingDB Entry DOI: 10.7270/Q2PZ5C72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck and Center for Molecular Biosciences Innsbruck-CMBI Curated by ChEMBL | Assay Description Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane | Bioorg Med Chem 18: 5071-80 (2010) Article DOI: 10.1016/j.bmc.2010.05.071 BindingDB Entry DOI: 10.7270/Q2XP75XQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University La Sapienza Curated by ChEMBL | Assay Description In vitro agonistic activity against opioid receptor delta of mouse vas deferens | J Med Chem 48: 3372-8 (2005) Article DOI: 10.1021/jm040894o BindingDB Entry DOI: 10.7270/Q2X92C3R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50326662 (10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human DOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b01327 BindingDB Entry DOI: 10.7270/Q2RB7870 | |||||||||||
More data for this Ligand-Target Pair |