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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM215448'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM215448
PNG
(US9296745, 3)
Show SMILES O=C([C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)-c1cccc(c1)-n1cccn1)N1CCCC1 |r|
Show InChI InChI=1/C25H27N7O/c33-25(30-12-1-2-13-30)19-7-4-14-31(17-19)22-10-9-21-24(28-22)29-23(27-21)18-6-3-8-20(16-18)32-15-5-11-26-32/h3,5-6,8-11,15-16,19H,1-2,4,7,12-14,17H2,(H,27,28,29)/t19-/s2
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PC cid
PC sid
UniChem
US Patent
n/an/a 4.82n/an/an/an/a7.425



Pfizer Inc.

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...


US Patent US9296745 (2016)


BindingDB Entry DOI: 10.7270/Q25719VW
More data for this
Ligand-Target Pair