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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 2' and Ligand = 'BDBM215484'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM215484
PNG
(US9296745, 39)
Show SMILES O=C([C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)-c1coc(n1)-c1ccccc1)N1CCCC1 |r|
Show InChI InChI=1/C25H26N6O2/c32-25(30-12-4-5-13-30)18-9-6-14-31(15-18)21-11-10-19-22(28-21)29-23(26-19)20-16-33-24(27-20)17-7-2-1-3-8-17/h1-3,7-8,10-11,16,18H,4-6,9,12-15H2,(H,26,28,29)/t18-/s2
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PC cid
PC sid
UniChem
US Patent
n/an/a 6.85n/an/an/an/a7.425



Pfizer Inc.

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...


US Patent US9296745 (2016)


BindingDB Entry DOI: 10.7270/Q25719VW
More data for this
Ligand-Target Pair