Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Lactobacillus casei) | BDBM50022388 (2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase of Lactobacillus casei | J Med Chem 31: 150-3 (1988) BindingDB Entry DOI: 10.7270/Q2GX4C44 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |