Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Mus musculus (Mouse)) | BDBM50023682 (2-{4-[(2,4-Diamino-5-methyl-7-phenyl-pyrido[2,3-d]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >0.00400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cells | J Med Chem 31: 1209-15 (1988) BindingDB Entry DOI: 10.7270/Q2930S6N | |||||||||||
More data for this Ligand-Target Pair |