Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Rattus norvegicus (rat)) | BDBM50026274 (2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-methyl-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of rat liver DHFR assayed spectrophotometrically at 340 nM | J Med Chem 28: 209-15 (1985) BindingDB Entry DOI: 10.7270/Q20C4TS5 | |||||||||||
More data for this Ligand-Target Pair |