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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A)' and Ligand = 'BDBM15356'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A)


(Plasmodium falciparum)
BDBM15356
PNG
(1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...)
Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



University of Texas Southwestern Medical Center



Assay Description
The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...


J Biol Chem 280: 21847-53 (2005)


Article DOI: 10.1074/jbc.M501100200
BindingDB Entry DOI: 10.7270/Q21G0JH3
More data for this
Ligand-Target Pair