Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydroorotate dehydrogenase (quinone), mitochondrial' and Ligand = 'BDBM24411'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM24411 (5-methyl-N-(naphthalen-1-yl)-[1,2,4]triazolo[1,5-a...) Show SMILES Cc1cc(Nc2cccc3ccccc23)n2ncnc2n1 Show InChI InChI=1S/C16H13N5/c1-11-9-15(21-16(19-11)17-10-18-21)20-14-8-4-6-12-5-2-3-7-13(12)14/h2-10,20H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	8.0	20
University of Texas Southwestern Medical Center at Dallas					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 51: 3649-53 (2008) Article DOI: 10.1021/jm8001026 BindingDB Entry DOI: 10.7270/Q2PV6HNF
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