Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM11694'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro test for inhibitory activity against human dipeptidyl peptidase IV.				Bioorg Med Chem Lett 6: 1163-1166 (1996) Article DOI: 10.1016/0960-894X(96)00190-4 BindingDB Entry DOI: 10.7270/Q279455Q
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity towards Dipeptidyl peptidase IV (DPP-IV)				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cells				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cells				J Med Chem 45: 2362-5 (2002) BindingDB Entry DOI: 10.7270/Q2930SHP
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Rattus norvegicus (rat))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasma				J Med Chem 45: 2362-5 (2002) BindingDB Entry DOI: 10.7270/Q2930SHP
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Rattus norvegicus (rat))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from rat plasma				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from human plasma				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasma				J Med Chem 45: 2362-5 (2002) BindingDB Entry DOI: 10.7270/Q2930SHP
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	8.0	37
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				J Med Chem 49: 373-80 (2006) Article DOI: 10.1021/jm0507781 BindingDB Entry DOI: 10.7270/Q28W3BJH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibitory concentration against Dipeptidyl-peptidase IV [DPP-IV]				Bioorg Med Chem Lett 15: 3271-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.051 BindingDB Entry DOI: 10.7270/Q2RF5TJX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				Bioorg Med Chem Lett 15: 687-91 (2005) Article DOI: 10.1016/j.bmcl.2004.11.023 BindingDB Entry DOI: 10.7270/Q2XG9PDW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Bos taurus)	BDBM11694 ((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C13H21N3O/c14-9-11-7-4-8-16(11)13(17)12(15)10-5-2-1-3-6-10/h10-12H,1-8,15H2/t11-,12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Dipeptidyl-peptidase II (DPP-II) extracted from bovine kidney homogenate				J Med Chem 45: 2362-5 (2002) BindingDB Entry DOI: 10.7270/Q2930SHP
					More data for this Ligand-Target Pair