BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM50228407'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 4 (Sus scrofa (pig))	BDBM50228407 (8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assay				ACS Med Chem Lett 4: 768-72 (2013) Article DOI: 10.1021/ml400171b BindingDB Entry DOI: 10.7270/Q2HQ41BX
Sanofi-Aventis Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50228407 (8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibition of human DPP4				ACS Med Chem Lett 4: 768-72 (2013) Article DOI: 10.1021/ml400171b BindingDB Entry DOI: 10.7270/Q2HQ41BX
Sanofi-Aventis Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50228407 (8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assay				ACS Med Chem Lett 4: 768-72 (2013) Article DOI: 10.1021/ml400171b BindingDB Entry DOI: 10.7270/Q2HQ41BX
Sanofi-Aventis Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50228407 (8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH & Co. KG Curated by ChEMBL					Assay Description Inhibition of human DPP4 in Caco2 cells by fluorescene assay				J Med Chem 50: 6450-3 (2007) Article DOI: 10.1021/jm701280z BindingDB Entry DOI: 10.7270/Q2639PGG
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Sus scrofa (pig))	BDBM50228407 (8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Curated by ChEMBL					Assay Description Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assay				ACS Med Chem Lett 4: 768-72 (2013) Article DOI: 10.1021/ml400171b BindingDB Entry DOI: 10.7270/Q2HQ41BX
Sanofi-Aventis Curated by ChEMBL					More data for this Ligand-Target Pair