new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase VIII' and Ligand = 'BDBM50324506'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50324506
PNG
(6-(aminomethyl)-5-(2,4-dichlorophenyl)-N-(furan-2-...)
Show SMILES Cc1nc2nc(cn2c(c1CN)-c1ccc(Cl)cc1Cl)C(=O)NCc1ccco1 |(7.8,-1.45,;6.49,-2.27,;5.14,-1.55,;3.84,-2.36,;2.36,-1.92,;1.5,-3.2,;2.43,-4.42,;3.89,-3.9,;5.24,-4.63,;6.55,-3.82,;7.91,-4.54,;9.21,-3.73,;5.21,-6.16,;3.86,-6.9,;3.83,-8.44,;5.15,-9.24,;5.12,-10.78,;6.5,-8.48,;6.52,-6.94,;7.87,-6.2,;-.05,-3.24,;-.86,-1.94,;-.77,-4.6,;-2.31,-4.64,;-3.04,-6,;-2.63,-7.49,;-3.9,-8.34,;-5.12,-7.39,;-4.59,-5.95,)|
Show InChI InChI=1S/C20H17Cl2N5O2/c1-11-15(8-23)18(14-5-4-12(21)7-16(14)22)27-10-17(26-20(27)25-11)19(28)24-9-13-3-2-6-29-13/h2-7,10H,8-9,23H2,1H3,(H,24,28)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.40n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


J Med Chem 53: 5620-8 (2010)


Article DOI: 10.1021/jm100634a
BindingDB Entry DOI: 10.7270/Q2S182PX
More data for this
Ligand-Target Pair