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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase VIII' and Ligand = 'BDBM50359374'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50359374
PNG
(CHEMBL1929395)
Show SMILES Cc1cc2nc(C)c(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 |r|
Show InChI InChI=1S/C21H29N7O2/c1-13-9-17-25-14(2)19(15(3)28(17)26-13)20(30)23-12-21(4,5)24-11-18(29)27-8-6-7-16(27)10-22/h9,16,24H,6-8,11-12H2,1-5H3,(H,23,30)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Sanwa Kagaku Kenkyusho Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...


Bioorg Med Chem 19: 7221-7 (2011)


Article DOI: 10.1016/j.bmc.2011.09.043
BindingDB Entry DOI: 10.7270/Q2862GVX
More data for this
Ligand-Target Pair