Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1' and Ligand = 'BDBM28044'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM28044 (7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...) Show SMILES NC(=O)c1cc2c(cnc(N)c2s1)-c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C20H15N3OS/c21-19-18-15(10-17(25-18)20(22)24)16(11-23-19)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-11H,(H2,21,23)(H2,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description MEK1 cascade HTRF assays were carried out using inactive Erk2 as a downstream kinase with biotin-MBP protein as the final substrate. The reaction was...				Bioorg Med Chem Lett 19: 1722-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.088 BindingDB Entry DOI: 10.7270/Q2VH5M4P
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