Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1' and Ligand = 'BDBM50066139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50066139 (CHEMBL3400285) Show SMILES CN(C)C(=O)Oc1ccc2c(C)c(Cc3cccc(NS(=O)(=O)CCCCl)c3)c(=O)oc2c1 Show InChI InChI=1S/C23H25ClN2O6S/c1-15-19-9-8-18(31-23(28)26(2)3)14-21(19)32-22(27)20(15)13-16-6-4-7-17(12-16)25-33(29,30)11-5-10-24/h4,6-9,12,14,25H,5,10-11,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
The University of Michigan Medical School Curated by ChEMBL					Assay Description Inhibition of MEK1 (unknown origin)				Bioorg Med Chem 23: 1386-94 (2015) Article DOI: 10.1016/j.bmc.2015.02.053 BindingDB Entry DOI: 10.7270/Q2G162H4
					More data for this Ligand-Target Pair