Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 1' and Ligand = 'BDBM50337928'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50337928 ((R)-3-(2,3-dihydroxypropyl)-5-(4-ethynyl-2-fluorop...) Show SMILES Cn1c2ncn(C[C@@H](O)CO)c(=O)c2c(Nc2ccc(cc2F)C#C)c(F)c1=O |r| Show InChI InChI=1S/C19H16F2N4O4/c1-3-10-4-5-13(12(20)6-10)23-16-14-17(24(2)19(29)15(16)21)22-9-25(18(14)28)7-11(27)8-26/h1,4-6,9,11,23,26-27H,7-8H2,2H3/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego Curated by ChEMBL					Assay Description Inhibition of MEK1 by IMAP assay				Bioorg Med Chem Lett 21: 1315-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.071 BindingDB Entry DOI: 10.7270/Q2833SB8
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