Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human)) | BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
OSI Pharmaceuticals, Inc Curated by ChEMBL | Assay Description Inhibition of MEK1 | Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH | |||||||||||
More data for this Ligand-Target Pair |