Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK2' and Ligand = 'BDBM317455'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM317455 (4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...) Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1 Show InChI InChI=1S/C26H27N5O4/c1-27-24(33)16-9-12-20(21(13-16)34-2)29-26-30-23-22(25(31-26)35-18-5-3-4-6-18)19(14-28-23)15-7-10-17(32)11-8-15/h7-14,18,32H,3-6H2,1-2H3,(H,27,33)(H2,28,29,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.9	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
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