Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241227'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241227 (US10479788, Example 69 | US11046688, Example 69 | ...) Show SMILES COc1cc(ccc1Nc1ncc2ccnc(NC3CCOCC3)c2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H25N7O2/c1-30-14-17(13-26-30)15-3-4-19(20(11-15)31-2)28-23-25-12-16-5-8-24-22(21(16)29-23)27-18-6-9-32-10-7-18/h3-5,8,11-14,18H,6-7,9-10H2,1-2H3,(H,24,27)(H,25,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US10479788 (2019) BindingDB Entry DOI: 10.7270/Q2BP055X
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241227 (US10479788, Example 69 | US11046688, Example 69 | ...) Show SMILES COc1cc(ccc1Nc1ncc2ccnc(NC3CCOCC3)c2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H25N7O2/c1-30-14-17(13-26-30)15-3-4-19(20(11-15)31-2)28-23-25-12-16-5-8-24-22(21(16)29-23)27-18-6-9-32-10-7-18/h3-5,8,11-14,18H,6-7,9-10H2,1-2H3,(H,24,27)(H,25,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	25
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US9409907 (2016) BindingDB Entry DOI: 10.7270/Q2C24VB2
					More data for this Ligand-Target Pair