Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241314'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241314 (US10479788, Example 158 | US11046688, Example 158 ...) Show SMILES COc1cc(ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1)-c1cnc(C)n1C Show InChI InChI=1S/C25H31N7O2/c1-15-10-18-12-27-24(31-22(18)23(29-15)28-14-25(3,4)34-7)30-19-9-8-17(11-21(19)33-6)20-13-26-16(2)32(20)5/h8-13H,14H2,1-7H3,(H,28,29)(H,27,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US10479788 (2019) BindingDB Entry DOI: 10.7270/Q2BP055X
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241314 (US10479788, Example 158 | US11046688, Example 158 ...) Show SMILES COc1cc(ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1)-c1cnc(C)n1C Show InChI InChI=1S/C25H31N7O2/c1-15-10-18-12-27-24(31-22(18)23(29-15)28-14-25(3,4)34-7)30-19-9-8-17(11-21(19)33-6)20-13-26-16(2)32(20)5/h8-13H,14H2,1-7H3,(H,28,29)(H,27,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	25
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US9409907 (2016) BindingDB Entry DOI: 10.7270/Q2C24VB2
					More data for this Ligand-Target Pair