Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241368'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241368 (US9409907, 142) Show SMILES COc1cc(ccc1NC1=Nc2c(N)nccc2CN1C[C@]1(C)CCOC1)-c1cnn(C)c1 |t:10| Show InChI InChI=1S/C24H29N7O2/c1-24(7-9-33-15-24)14-31-13-17-6-8-26-22(25)21(17)29-23(31)28-19-5-4-16(10-20(19)32-3)18-11-27-30(2)12-18/h4-6,8,10-12H,7,9,13-15H2,1-3H3,(H2,25,26)(H,28,29)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	25
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US9409907 (2016) BindingDB Entry DOI: 10.7270/Q2C24VB2
					More data for this Ligand-Target Pair