Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B' and Ligand = 'BDBM50236541'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50236541 (CHEMBL4067661) Show SMILES NC(=O)Nc1ccc(cc1)-c1cnc2[nH]cc(-c3ccc(O)cc3)c2c1 Show InChI InChI=1S/C20H16N4O2/c21-20(26)24-15-5-1-12(2-6-15)14-9-17-18(11-23-19(17)22-10-14)13-3-7-16(25)8-4-13/h1-11,25H,(H,22,23)(H3,21,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
QIMR Berghofer Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of DYRK1B (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation counting				J Med Chem 60: 2052-2070 (2017) Article DOI: 10.1021/acs.jmedchem.6b01840 BindingDB Entry DOI: 10.7270/Q2ST7S3J
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