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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dynamin-1' and Ligand = 'BDBM50055861'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dynamin-1


(Homo sapiens (Human))
BDBM50055861
PNG
(CHEMBL3329968)
Show SMILES OC(=O)c1ccc(NC2=CC(=O)C(Nc3ccc(cc3)C(O)=O)=CC2=O)cc1 |c:23,t:8|
Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-7-3-12(4-8-14)20(27)28)18(24)9-15(17)21-13-5-1-11(2-6-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...


Eur J Med Chem 85: 191-206 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.070
BindingDB Entry DOI: 10.7270/Q28G8NCR
More data for this
Ligand-Target Pair