Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dynamin-1' and Ligand = 'BDBM50268961'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50268961 (2-Cyano-N-hexyl-3-[1-(3-dimethylaminopropyl)-2-met...) Show SMILES CCCCCCNC(=O)C(=C\c1c(C)n(CCCN(C)C)c2ccccc12)\C#N Show InChI InChI=1S/C24H34N4O/c1-5-6-7-10-14-26-24(29)20(18-25)17-22-19(2)28(16-11-15-27(3)4)23-13-9-8-12-21(22)23/h8-9,12-13,17H,5-7,10-11,14-16H2,1-4H3,(H,26,29)/b20-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 1-mediated endocytosis internalization of Tf-A594 in human U2OS cells pretreated for 30 mins				J Med Chem 52: 3762-73 (2009) Article DOI: 10.1021/jm900036m BindingDB Entry DOI: 10.7270/Q28W3D79
					More data for this Ligand-Target Pair