BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dynamin-2' and Ligand = 'BDBM50316543'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dynamin-2 (Homo sapiens (Human))	BDBM50316543 (CHEMBL1094197 \| N,N'-(Propane-1,3-diyl)bis(6,7-dih...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assay				J Med Chem 53: 4094-102 (2010) Article DOI: 10.1021/jm100119c BindingDB Entry DOI: 10.7270/Q2PZ5903
The University of Newcastle Curated by ChEMBL					More data for this Ligand-Target Pair
Dynamin-2 (Homo sapiens (Human))	BDBM50316543 (CHEMBL1094197 \| N,N'-(Propane-1,3-diyl)bis(6,7-dih...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...				J Med Chem 53: 4094-102 (2010) Article DOI: 10.1021/jm100119c BindingDB Entry DOI: 10.7270/Q2PZ5903
The University of Newcastle Curated by ChEMBL					More data for this Ligand-Target Pair