Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31211'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31211 (2-phenoxybenzoyltryptophan derivative, R2C1) Show SMILES OC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C24H19ClN2O4/c25-16-10-11-18-15(14-26-20(18)13-16)12-21(24(29)30)27-23(28)19-8-4-5-9-22(19)31-17-6-2-1-3-7-17/h1-11,13-14,21,26H,12H2,(H,27,28)(H,29,30)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	-29.6	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
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