Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31216'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31216 (2-phenoxybenzoyltryptophan derivative, R3C2) Show SMILES OC(=O)[C@H](Cc1cn(C(=O)CCC2CCCC2)c2cc(F)ccc12)NC(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C32H31FN2O5/c33-23-15-16-25-22(20-35(28(25)19-23)30(36)17-14-21-8-4-5-9-21)18-27(32(38)39)34-31(37)26-12-6-7-13-29(26)40-24-10-2-1-3-11-24/h1-3,6-7,10-13,15-16,19-21,27H,4-5,8-9,14,17-18H2,(H,34,37)(H,38,39)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	400	-36.3	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
					More data for this Ligand-Target Pair