Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31282'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31282 (Chalcone derivative, L) Show SMILES CCC(C)Cc1ccc(OCC(O)=O)c(Cl)c1Cl Show InChI InChI=1S/C13H16Cl2O3/c1-3-8(2)6-9-4-5-10(13(15)12(9)14)18-7-11(16)17/h4-5,8H,3,6-7H2,1-2H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.50E+5	n/a	n/a	n/a	7.4	23
Max Planck Institute					Assay Description NMR measurements consisted of monitoring changes in chemical shifts and line widths of the backbone amide resonances of uniformly 15N-enriched MDM2 s...				Biochemistry 40: 336-44 (2001) Article DOI: 10.1021/bi000930v BindingDB Entry DOI: 10.7270/Q2GQ6W3K
					More data for this Ligand-Target Pair