Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50016475'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50016475 (CHEMBL3265100) Show SMILES COc1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)c(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H15ClN2O2/c1-28-18-8-6-16(19(12-18)15-4-2-14(13-25)3-5-15)10-21-20-11-17(24)7-9-22(20)26-23(21)27/h2-12H,1H3,(H,26,27)/b21-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Science and Peking Union Medical College Curated by ChEMBL					Assay Description Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assay				Eur J Med Chem 81: 277-88 (2014) Article DOI: 10.1016/j.ejmech.2014.05.027 BindingDB Entry DOI: 10.7270/Q2736SGW
					More data for this Ligand-Target Pair