Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50163926'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50163926 ((E)-N-[(S)-Carbamoyl-(4-chloro-phenyl)-methyl]-N-[...) Show SMILES C[C@@H](N([C@H](C(N)=O)c1ccc(Cl)cc1)C(=O)\C=C\c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H22Cl2N2O2/c1-17(19-8-12-21(26)13-9-19)29(23(30)16-7-18-5-3-2-4-6-18)24(25(28)31)20-10-14-22(27)15-11-20/h2-17,24H,1H3,(H2,28,31)/b16-7+/t17-,24+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity between MDM2 and p53 protein in fluorescence peptide assay				Bioorg Med Chem Lett 15: 1857-61 (2005) Article DOI: 10.1016/j.bmcl.2005.02.018 BindingDB Entry DOI: 10.7270/Q21G0KRN
					More data for this Ligand-Target Pair