Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50163927'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50163927 (CHEMBL425528 | [(3-Iodo-benzoyl)-(4-trifluoromethy...) Show SMILES OC(=O)C(N(Cc1ccc(cc1)C(F)(F)F)C(=O)c1cccc(I)c1)c1ccccc1 Show InChI InChI=1S/C23H17F3INO3/c24-23(25,26)18-11-9-15(10-12-18)14-28(21(29)17-7-4-8-19(27)13-17)20(22(30)31)16-5-2-1-3-6-16/h1-13,20H,14H2,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity between MDM2 and p53 protein in fluorescence peptide assay				Bioorg Med Chem Lett 15: 1857-61 (2005) Article DOI: 10.1016/j.bmcl.2005.02.018 BindingDB Entry DOI: 10.7270/Q21G0KRN
					More data for this Ligand-Target Pair