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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50339354'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM50339354
PNG
((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxypropoxy)-2-(4...)
Show SMILES OCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H21ClN2O5/c25-19-10-8-18(9-11-19)24(32-15-3-14-28)22-5-2-1-4-21(22)23(29)26(24)16-17-6-12-20(13-7-17)27(30)31/h1-2,4-13,28H,3,14-16H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 450n/an/an/an/an/an/a



Newcastle University

Curated by ChEMBL


Assay Description
Inhibition of Mdm2 -p53 protein interaction by ELISA


J Med Chem 54: 1233-43 (2011)


Article DOI: 10.1021/jm1011929
BindingDB Entry DOI: 10.7270/Q29K4BHN
More data for this
Ligand-Target Pair