Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50339364'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339364 ((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxymethylbenzylo...) Show SMILES OCc1cccc(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C29H23ClN2O5/c30-24-12-10-23(11-13-24)29(37-19-22-5-3-4-21(16-22)18-33)27-7-2-1-6-26(27)28(34)31(29)17-20-8-14-25(15-9-20)32(35)36/h1-16,33H,17-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair