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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'ELAV-like protein 1' and Ligand = 'BDBM50326009'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326009
PNG
(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3
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MCE
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Article
PubMed
n/an/an/a 14n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation ...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326009
PNG
(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3
PDB
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CHEMBL
MCE
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Article
PubMed
n/an/an/a 0.100n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spe...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326009
PNG
(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3
PDB
MMDB

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CHEMBL
MCE
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/a 0.100n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326009
PNG
(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3
PDB
MMDB

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CHEMBL
MCE
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PC sid
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Article
PubMed
n/an/an/a 420n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Binding affinity recombinant HuR RRM1/RRM2 domain by confocal fluctuation spectroscopy


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326009
PNG
(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12
Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 230n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spec...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair