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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'ELAV-like protein 1' and Ligand = 'BDBM50326010'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326010
PNG
(CHEMBL1242196 | Dehydromutactin)
Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1
Show InChI InChI=1S/C16H12O5/c1-8-5-12(19)16-10(3-2-4-11(16)18)15(8)13-6-9(17)7-14(20)21-13/h2-7,17-19H,1H3
PDB
MMDB

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PC sid
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Article
PubMed
n/an/an/a 0.0100n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectros...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326010
PNG
(CHEMBL1242196 | Dehydromutactin)
Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1
Show InChI InChI=1S/C16H12O5/c1-8-5-12(19)16-10(3-2-4-11(16)18)15(8)13-6-9(17)7-14(20)21-13/h2-7,17-19H,1H3
PDB
MMDB

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PC sid
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Article
PubMed
n/an/an/a 0.100n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectros...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326010
PNG
(CHEMBL1242196 | Dehydromutactin)
Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1
Show InChI InChI=1S/C16H12O5/c1-8-5-12(19)16-10(3-2-4-11(16)18)15(8)13-6-9(17)7-14(20)21-13/h2-7,17-19H,1H3
PDB
MMDB

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PC sid
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Article
PubMed
n/an/an/a 9n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectrosc...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326010
PNG
(CHEMBL1242196 | Dehydromutactin)
Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1
Show InChI InChI=1S/C16H12O5/c1-8-5-12(19)16-10(3-2-4-11(16)18)15(8)13-6-9(17)7-14(20)21-13/h2-7,17-19H,1H3
PDB
MMDB

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Article
PubMed
n/an/an/a 6n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation sp...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair
ELAV-like protein 1


(Homo sapiens (Human))
BDBM50326010
PNG
(CHEMBL1242196 | Dehydromutactin)
Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1
Show InChI InChI=1S/C16H12O5/c1-8-5-12(19)16-10(3-2-4-11(16)18)15(8)13-6-9(17)7-14(20)21-13/h2-7,17-19H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 9n/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectrosc...


Nat Chem Biol 3: 508-15 (2007)


Article DOI: 10.1038/nchembio.2007.14
BindingDB Entry DOI: 10.7270/Q2QN670V
More data for this
Ligand-Target Pair