Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50031822 (CHEMBL3360895) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Competitive inhibition of human NPP1 using p-Nph-5'-TMP as substrate by Lineweaver-Burk plot analysis | J Med Chem 57: 10080-100 (2014) Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50031822 (CHEMBL3360895) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Inhibition of human NPP1 using p-Nph-5'-TMP as substrate | J Med Chem 57: 10080-100 (2014) Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50031822 (CHEMBL3360895) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Competitive inhibition of human NPP1 using ATP as substrate by Lineweaver-Burk plot analysis | J Med Chem 57: 10080-100 (2014) Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S | |||||||||||
More data for this Ligand-Target Pair |